I wiped my Mac earlier today, and everything seems to be in working order, more or less. I noted a couple of my tweaks before on my wiki, and I forgot some other hidden settings that I like to have.
Two of my favorite tweaks: Increase the mouse sensitivity beyond what macOS allows, and get rid of the delay on the dock before it appears, when it’s set to auto-hide.
For the mouse, read the current sensitivity: defaults read -g com.apple.mouse.scaling in the terminal. The max allowed through the settings is 3, but I set it to 5 with defaults write -g com.apple.mouse.scaling 5 as I have a small area to move my USB Bluetooth mouse.
And for the no-delay Dock, two commands: defaults write com.apple.dock autohide-delay -float 0 and defaults write com.apple.dock autohide-time-modifier -float 0. Nice and snappy. Use killall Dock to restart the Dock for this to take effect.
Do you have any hidden tweaks for your Mac?